Most Beautiful 2009: After being diagnosed with breast cancer and undergoing a double mastectomy a year earlier, the actress was learning to appreciate her new body: “I don’t have to wear a bra!” she said. “And the gals look good in tank tops.” Helping her heal: boyfriend Martyn LeNoble, who made her feel “beautiful.”
Now: Applegate, 43, who once told Cosmopolitan, “I never looked in the mirror and thought I was a pretty girl,” married LeNoble (with whom she has daughter, Sadie, 4) in February 2013. Also in 2013, she returned to the big screen in Anchorman 2: The Legend Continues. “I kind of thought, ‘It s 10 years later, if I ve got 10 more pounds on me than [in] the first one then I think it s completely acceptable,’ she told Fitness.